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diagnosis rheumatology algorithm cns disease hematology hepatology injury liver neurology acute agglutinin aids anemia antibodies associations autoantibodies causes cold diseases
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Parenchyma • Infectious ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... #Injury #Differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV ... Prunelle Getten #AdultOnset
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... Anti-mitochondrial (AMA ... biliary cirrhosis (PBC ... Celiac disease Anti-GBM ... diseases #diagnosis #table
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Injury: • Infectious ... HBV, HCV, HEV, EBV ... Celiac disease • Autoimmune ... : Autoimmune hepatitis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
, autoimmune disorder ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... younger pts) Differential ... Disorders Such As
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... /l is regarded as ... rav7ks #CNS #Infections ... #differential #
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... • Symptoms: AMS ... symptoms such as ... effect/Edema • EBV ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • Viral infections ... acute HIV, HBV, EBV ... Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... Gap #ProteinGap #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tenderness → Consider infectious ... • ANA < 20 % IBM ... Other Diseases: • PBC ... #rheumatology #differential
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