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diagnosis algorithm rheumatology causes hepatology injury liver lymphoma acute antibodies associations autoantibodies autoimmune classification comparison diseases erythematosus gap globulin lad
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Infectious • EBV ... Tuberculosis • Hepatitis ... Algorithm #Causes #Hematology ... #Oncology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... C, A, E, B, D, EBV ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Injury #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV), EBV ... lymphadenopathy, mass ... • Other hematologic ... NonHodgkins #comparison #oncology ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... HBV, HCV, HEV, EBV ... , PBC, PSC, IgG4 ... #differential # ... diagnosis #algorithm #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Anterior mediastinal mass ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
SLE, autoimmune hepatitis ... ) - Autoimmune hepatitis ... biliary cirrhosis (PBC ... - Scleroderma (Diffuse ... Celiac disease Anti-GBM
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
acute HIV, HBV, EBV ... Sarcoidosis) • Liver ... , PBC, PSC, Viral ... Gap #ProteinGap #differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... pneumonitis • Diffuse ... Noninfectious hepatitis ... Antiribosomal P, APLA, PAC ... cyclophosphamide) • Hodgkin
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... • ANA < 20 % IBM ... Other Diseases: • PBC ... , autoimmune hepatitis ... #differential #
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