4 results
Algorithm for Suspected SVC Syndrome

SVC syndrome suspected: Facial/arm/neck edema, distended neck/chest veins, facial plethora, dyspnea, cough,
SVC Syndrome ... SVC syndrome suspected ... Syndrome Grading ... #Syndrome #Algorithm ... #diagnosis #management
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
heart is pounding, racing ... or sinus node dysfunction ... (sick sinus syndrome ... Wolff-Parkinson-White syndrome ... palpitations: PVC
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... • Steroids: IV ... severe APLS, organ dysfuxtion ... APML #diagnosis #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... progressive organ dysfunction ... Cholangitis - mimics PSC ... complement • Classification