213 results
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... Low SvO2 → Low PaO2 ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology
Respiratory Oxygenation Cycle - Pathophysiology
PO2 and PCO2

By @rev.med

#Respiratory #Oxygenation #Cycle #circulation #pathophysiology
Oxygenation Cycle - Pathophysiology ... PO2 and PCO2 By ... #circulation #pathophysiology
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Simplified ... /0.8)] - PaO2 Normal ... Hypoxia #hypoxemia #differential
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... tissue): • ↑ H+ (Acid ... ) • ↑ PCO2 • ... Dissociation #Curve #pathophysiology
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... - Differential ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... AcidBase #Disorders #Differential
Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
Acid Base Disorders ... CI-, HCO3-, PH, pCO2 ... diagnoses using the differentials ... joshsteinbergMD #Acid ... Worksheet #diagnosis #differential
Pathways Involved in Protein and Amino Acid Metabolism in Chronic Kidney Disease. The tricarboxylic acid (TCA)
Protein and Amino Acid ... tricarboxylic acid ... metabolize amino acids ... products of amino acid ... #Pathophysiology
PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A
- Approach to Acid-Base ... pH L - Labs: PCO2 ... PLACO #AcidBase #Acid
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Differentials? ... 35-45 mmHg • PaO2 ... ABG #bloodgas #Acid ... Base #Gas #VBG #differential
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
to filter uric acid ... like lactic acid ... and keto-acids) ... secretion of uric acid ... Hyperuricemia #Pathophysiology