183 results
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
O2 is inspired) PAO2 ... hypoxia) - Low PaO2 ... Low SvO2 → Low PaO2 ... Low SvO2 → Low PaO2 ... #differential #diagnosis
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Normal ... : Atelectasis, ARDS ... #differential #diagnosis
Markers of Organ Dysfunction in Severe Sepsis 
Altered consciousness 
Confusion 
Psychosis 

Tachycardia 
Hypotension 
Altered CVP 
Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... 90% PaO2/FiO2 300% ... Protein C #Diagnosis ... #CriticalCare #Diagnosis
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... Interpretation #AcidBase ... #Diagnosis #Compensation
PROSEVA definition of ARDS
Thus, the PROSEVA trial essentially modifies the Berlin definition of ARDS, with the
definition of ARDS ... definition of ARDS ... requirement that the PaO2 ... requires that the PaO2 ... #Diagnosis #CriticalCare
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
- Differential Diagnosis ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... < 35 mmHg) #AcidBase ... #Differential #Diagnosis
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2, pCO2 ... #Diagnosis #Nephro ... #AcidBase #Acidosis
PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A
pH L - Labs: PCO2 ... jadav_md #PLACO #AcidBase ... #Acid #Base #diagnosis
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) 
- Respiratory symptoms must have begun within one
Distress Syndrome (ARDS ... severity of the ARDS ... - 200 mm Hg < PaO2 ... >= 5cm H2O #ARDS ... Definition #Criteria #Diagnosis
Understanding & Treating ARDS - Acute Respiratory Distress Syndrome

•  Timing - within one week of
Understanding & Treating ARDS ... Impaired Oxygenation PaO2 ... @nickmmark #ARDS ... Acute #Syndrome #Diagnosis