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Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... Low SvO2 → Low PaO2 ... Low SvO2 → Low PaO2 ... sepsis) - High PaO2
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Simplified ... /0.8)] - PaO2 Normal ... : Atelectasis, ARDS
Markers of Organ Dysfunction in Severe Sepsis Altered consciousness Confusion Psychosis Tachycardia Hypotension Altered CVP Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... <70mmHg SaO2 < ... 90% PaO2/FiO2 300%
Perform computations online at: ScyMed.com 6th ED ICU-card «ICU, Formulas & Drugs» HEMODYNAMIC PATTERNS Condition SAP CVP PAP PCWP CO C(a-v)02 PVR SVR Hypovolemic shock ↓ ↓ ↓ ↓ ↓ ↑ ↑ ↑ Cardiogenic shock ↓ 1 ↑ 1 1 ↑ Septic shock ↓ ↓ ↓ ↓ ↑ ↓ ↓ ↓ Cardiac Tamponade . ↑ ↑ 1 ↓ → ↑ RV
-PECO2))/PaCO2 ... age-corrected PAO2 ... /R) | Pa02 80- ... ))+(Pa02*0.0031) ... )-(CvO2) Pa02
PROSEVA definition of ARDS Thus, the PROSEVA trial essentially modifies the Berlin definition of ARDS, with the
definition of ARDS ... definition of ARDS ... requirement that the PaO2 ... requires that the PaO2 ... #CriticalCare #ARDS
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 Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) - Respiratory symptoms must have begun within one
Distress Syndrome (ARDS ... severity of the ARDS ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2 ... >= 5cm H2O #ARDS
Mechanical ventilation in obese patients according to the i-STAR Algorithm Intubate • Anticipate difficult airway management and
5 cmH20 in non-ARDS ... and non-ARDS) ... > 7.25 in non-ARDS ... and ARDS, tolerate ... minimal to keep PaO2
Understanding & Treating ARDS - Acute Respiratory Distress Syndrome • Timing - within one week of
Understanding & Treating ARDS ... Impaired Oxygenation PaO2 ... @nickmmark #ARDS
Respiratory Oxygenation Cycle - Pathophysiology PO2 and PCO2 By @rev.med #Respiratory #Oxygenation #Cycle #circulation #pathophysiology
Pathophysiology PO2 ... and PCO2 By @rev.med
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet An acute diffuse, inflammatory lung injury, leading to
Distress Syndrome – ARDS ... on CT or CXR ● PaO2 ... sepsis-associated ARDS ... days after dx of ARDS ... RespiratoryDistress #Syndrome #ARDS
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