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Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... Low SvO2 → Low PaO2 ... summary #pulmonary #differential ... #diagnosis #causes
Markers of Organ Dysfunction in Severe Sepsis Altered consciousness Confusion Psychosis Tachycardia Hypotension Altered CVP Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... 90% PaO2/FiO2 300% ... Protein C #Diagnosis ... #CriticalCare #Diagnosis
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Normal ... Hypoxia #hypoxemia #differential ... #diagnosis
Hypoxemia vs Hypoxia Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal Hypoxia - Insufficient oxygen
arterial oxygen (PaO2 ... compensate for low PaO2 ... hypoxia #hypoxemia #differential ... #diagnosis #comparison
Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders - Differential ... Diagnosis Algorithm ... Respiratory Acidosis (pCO2 ... AcidBase #Disorders #Differential ... #Diagnosis #Algorithm
Acid Base Disorders Worksheet Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
CI-, HCO3-, PH, pCO2 ... Step 7: Make the diagnoses ... using the differentials ... Disorders #Worksheet #diagnosis ... #differential
Hepatopulmonary Syndrome HPS - Diagnosis: 1. Patients with liver disease 2. Alveolar-arterial oxygen gradient (AaP02) >15 mmHg
Syndrome HPS - Diagnosis ... Moderate HPS: ≥ 60 PaO2 ... Severe HPS: ≥ 50 PaO2 ... Very severe HPS: PaO2 ... Hepatopulmonary #Syndrome #diagnosis
ABG vs VBG: Arterial vs Venous Blood Gases ABG PROS: Tells you exactly what the arterial environment looks
looks like (pH, PaCO2 ... Comparison #pH #pCO2 ... #Diagnosis #Differences
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2 ... Interpretation #AcidBase #Diagnosis
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Differentials? ... 35-45 mmHg • PaO2 ... Diagnosis: Causes ... Interpretation #Diagnosis ... Base #Gas #VBG #differential
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