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Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
nociceptors -> Pain ... painful swelling -> Pain ... after > 1 hr • Blood ... -> Pain with motion ... JointDisease #JointPain #Diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... Noninflammatory • Bloody ... tumor • Non-bloody ... #Joint #Pain #MSK ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... : Is the pain from ... mainly or only during ... #Pain #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... taking a shower and moving ... - Autoimmune Rheumatologic ... #Diagnosis #MSK ... #rheumatology #
Illustrations showing elements of a shoulder assessment. Also included on a shoulder assessment would be determination
acromioclavicular joint ... tendon tenderness (using ... Pain in the anterior ... #Diagnosis #PhysicalExam
Metformin: Biguanide Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
the first-line medication ... effective in lowering blood ... The main counseling ... point for side ... #Metformin #Pharmacology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
phenomenon (20%) Joints ... lesions Abdominal pain ... Glomerulonephritis Myositis(5%) Blood ... signs #symptoms #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... arteritis • Bloody ... #pain #differential ... #diagnosis #rheumatology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
commonly used medications ... post-prandial blood ... injection site pain ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... • Peripheral blood ... uncovered incidentally during ... #Differential #diagnosis ... #hematology #eosinophilia
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