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anemia causes dermatology hemolytic algorithm arterial bleeding bruising classification cold dermatologic embolism erythematosus extravascular gpa granulomatosis lupus nonpalpable pathophysiology polyangiitis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... . primary cold agglutin ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: Vasculitis: ... • Ig A vasculitis ... HCV, HBV Not Vasculitis ... #Diagnosis #hematology ... #rheumatology #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Diagnosis: • hemolytic ... chills, flank pain ... #disease #hemolytic ... #anemia #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Congenital - Rare • Drugs ... • Steroids • Vasculitis ... • Disseminated Intravascular ... #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... scleritis • Palpable ... Skin -> causing palpable ... differential #diagnosis ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Pauci-immune vasculitis ... Diagnosis: Vasculitis ... Granulomatous vasculitis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... , drug reactions ... #Differential #Diagnosis ... #Rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... Myeloproliferative disease ... - Disseminated intravascular ... 19 - PNH - Vasculitis ... pathophysiology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... Arthritis: • Joint pain ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Rheumatology
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