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diagnosis differential systemic lupus sle vasculitis aids antimda5 arthritis autoantibodies autoimmune bronchiectasis classification dermatology dermatomyositis hiv infections infectiousdiseases lung mimickers
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... anti-NXP2 Abs Lung ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... pain (20%) Renal disease ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Arthritis #RA #Signs ... #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Nasal polyps and signs ... in the adjacent lung ... of the affected lung ... high-resolution chest CT
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Diagnosis Framework Disease ... • CT: Halo sign ... papules, pustules, erythematous ... Constitutional symptoms ... Infections #HIV #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... ischemia • Skin: Erythematous ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... , pancreas, stomach ... , pancreas, stomach
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