64 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... and Treatment Algorithm ... #HES #Hematology ... eosinophils #diagnosis ... #management #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... glucocorticoid treatment ... symptoms (eg, skin ... #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
and Management ... Secondary Causes ... #diagnosis #hematology ... #differential # ... management #eosinophils
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Leukocytoclastic Vasculitis Secondary ... drug eruptions, paraneoplastic ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology ... #causes
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Resolution > 15 days Differentials ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... #Diagnosis #hematology ... #nonpalpable #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Amyloidosis • Eosinophilic ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Methotrexate ILD Secondary ... Churg Strauss syndrome ... #ILD #diagnosis ... #differential # ... pulmonary #causes
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Polycythemia Vera Secondary ... Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... disease, Smoking ... #hematology