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differential management hematology classification acidosis anemia aplastic apml bronchiectasis cancer capillary cardiology chronic clarksons cll cord cryofibrinogenemia cryoglobulinemia cryoglobulins differentiation
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #hematology #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... : HCV infection, ... HBV infection, ... HIV infection ... 20% Sjögren's syndrome
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... - Viral (HIV, Influenza ... Dermatomyositis Clinical ... or compartment syndrome
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
bronchial wall injury ... • Mounier-Kuhn syndrome ... dyskinesia • Young syndrome ... , CCP, ANCA • HIV ... mycobacteria Treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... : Infection (sepsis ... Differentiation #Syndrome ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #workup #oncology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... of infections) ... Capillary #leak #syndrome ... #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... Advanced HIV (CD4 ... #infectiousdiseases
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... Lymphadenitis, pulmonary ... #Inflammatory #Syndrome
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... differential #algorithm
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