8 results
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... response to bacterial pathogens ... tissue -> Fatigue, fever ... #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... eradication of pathogen ... Pathogen cleared ... antibodies and causes ... activation of complement
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... presentation of pathogenic ... antibodies which can cause ... #Pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... : • 80% have fever ... Lung Abscess Pathogens ... #differential #causes
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
Majocchi’s Granuloma due to Trichophyton rubrum 
This is GMS stain and culture of a skin biopsy
No fever. ... tissues - mainly caused ... Majocchi granuloma pathogens ... rubrum most common pathogen ... Competent and compromised
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
(FMF) PATHOPHYSIOLOGY ... : The exact cause ... It causes the absolute ... not have a known pathogenic ... cause and are not