26 results
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... eradication of pathogen ... Pathogen cleared ... activation of complement ... #Gonorrhea #Pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
engulf foreign pathogens ... dead tissue • Complement ... System: opsonize pathogen ... activation of complement ... #Inflammation #pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... pathogens Bacterial ... activation -> Complement ... #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... (bacteria, viruses ... Opsonization: Abs coat pathogens ... Neutralization: Abs bind to pathogen ... Humoral #Immunity #pathophysiology
Acute Otitis Externa (Swimmer’s Ear): Pathogenesis and clinical findings
Pathogens = Pseudomonas aeruginosa (most common opportunistic), Staphylococcus,
clinical findings Pathogens ... . lysozyme) -> Bacterial ... -> Invasion of bacteria ... auditory canal -> Pathogen ... #SwimmersEar #pathophysiology
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings

Predisposing Factors:
 - Immunocompromised, Diabetes,
 - Elderly, Female
surfaces allow bacterial ... LUTI slide) -> Bacteria's ... parenchyma -> Bacterial ... proliferation Usual Pathogens ... UrinaryTractInfection #UUTI #Pathophysiology
Causes of Sore Throat / Rhinorrhea - Differential Diagnosis Algorithm
Common viral pathogens: Rhinovirus, Coronavirus, Influenza virus,
Differential Diagnosis Algorithm ... Common viral pathogens ... HIV Most common bacterial ... pathogen: Group ... Differential #Diagnosis #Algorithm
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... Hyponatremia - Diagnostic Algorithm ... #Hyponatremia #Algorithm ... #Pathophysiology ... #Differential #Nephrology
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
have a fastidious bacteria ... this be a non-bacterial ... pathogen? ... Diagnosis #Management #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm