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diagnosis hematology dermatomyositis leukemia management syndrome antimda5dm antinxp2 antinxp2dm behcet chronic cll dermpath lesions lymphocytic monoclonal myelodysplastic paraproteinemias semiology symptoms
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
EGPA • Solid cancers ... #semiology #signs ... #manifestations ... #pathology #lesions ... #differential
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... auricular papules Clinical ... severity of the disease ... #rheumatology # ... dermatology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Manifestations: ... gangrenosum • Cutaneous ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Manifestations: ... vasculitis) • Cutaneous ... ) Differential Diagnosis ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... syndrome: CNS manifestations ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... auricular papules Clinical ... had more severe disease ... diagnosis #management #rheumatology ... #dermatology
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