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diagnosis hematology dermpath gap globulin infections infectiousdiseases lesions leukemia mycobacteria myelodysplastic nontuberculous ntm paraproteinemias protein proteingap semiology signs vasculitis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... hypertrichosis, hyperpigmentation ... (-) hemolytic anemia ... #Monoclonal #Differential ... #Diagnosis #Oncology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... #manifestations ... #pathology #lesions ... #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... : CNS manifestations ... - infiltrates (anemia ... CLL -> Invade Skin ... #Oncology #Diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... gammopathy, and skin ... changes (POEMS syndrome ... ovarian tumors, lung cancers ... Gap #ProteinGap #differential
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... , alcohol, cancer ... Bone Marrow - Anemia ... : Clinical Manifestations ... NTM #Infections #differential
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