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rheumatology algorithm disease signs ulcerative agglutinin anemia behcet cryofibrinogenemia cryoglobulinemia dermpath hemolytic lesions management manifestations painless semiology symptoms syndrome types
Genital Skin Ulcers - Differential Diagnosis Algorithm Painful: • Herpes simplex • Haemophilus ducreyi (chancroid) • Behcet's
Genital Skin Ulcers ... - Differential ... Primary syphilis (chancre ... #skinrash #dermatology ... #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... ulcers - Glomerulonephritis ... Syndrome: • Clinical ... Henoch-Schönlein purpura) • Cutaneous ... #classification
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... insufficiency • Vasculitis ... #ulcerative #skinrash ... #dermatology #Differential ... #causes
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... #dermatology #semiology ... #pathology #lesions ... #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Viral Infection Clinical ... presentation) • Cutaneous ... Diagnosis Monoclonal ... hemolytic #anemia #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
) • Cutaneous Lesions ... matter, spinal cord ... Behcet disease) Differential ... Diagnosis: • Genital ... refractory disease : monoclonal
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... sensitivity • Painful ulcers ... • Negative causes ... Biopsy: Typical pathologic ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Recurrent oral and/or genital ... Serologies for Cryoglobulins ... differential #diagnosis ... classification
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