8 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... ulcers - Glomerulonephritis ... Syndrome: • Clinical ... Henoch-Schönlein purpura) • Cutaneous ... #classification
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... Mycosis fungoides (cutaneous ... #ulcerative #skinrash ... #dermatology #Differential ... #causes
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Clinical Presentation ... presentation) • Cutaneous ... Diagnosis Monoclonal ... hemolytic #anemia #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... #pathology #lesions ... #differential
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... sensitivity • Painful ulcers ... • Negative causes ... Biopsy: Typical pathologic ... hematology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... as non healing ulcer ... Indiana University Infectious ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... to exclude are infections ... Serologies for Cryoglobulins ... #diagnosis #rheumatology ... #classification
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... (buruli ulcer) ... disease, alcohol, cancer ... Hematologic malignancy ... #differential #