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transaminitis algorithm acute aflp causes chemistry cholestatic disease enzymes function hellp hepatocellular icp interpretation obstetrics patterns rvalue tests
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... ) • Non-hepatic ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
2-5x normal - Hemolysis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... pathology (low ... #differential # ... hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Injury #Differential ... Acute #algorithm #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
HELLP Syndrome (Hemolysis ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Injury: • Hepatic ... melanoma, myeloma • Pregnancy ... #injury #hepatitis ... #hepatology
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