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diagnosis rheumatology vasculitis algorithm als amyotrophic apml biliary cholangitis cirrhosis classification cord differentiation disease disorders gravis hepatology lateral leukostasis lysis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... objective evidence of neurologic ... #diagnosis #management ... #neurology #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... disease) Differential ... #management #signs ... #symptoms #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... bile ducts Differential ... cholestasis, Primary sclerosis ... diagnosis #workup #hepatology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... and signs below ... - Sarcoidosis, Behcet ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... Pathophysiology ... fasciculations Common Symptoms ... #neurology #diagnosis ... #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... /Cranial nerve pathology ... - Peek sign ... Gravis #diagnosis #management ... #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... Myelitis #diagnosis #management ... #neurology #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... , particularly scleritis ... purpura: strong sign ... Lab Tests: • CBC
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