71 results
diagnosis management signs differential hepatology treatment algorithm hematology syndrome workup causes cirrhosis nephrology biliary disorders endocrinology lymphoma pbc primary rheumatology
Plasmodium - Identification Algorithm • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
Multiple rings/RBC ... • P. malariae: ALL ... schizonts • P. vivax: ALL ... merozoites • P. ovale: ALL ... Identification #Algorithm #pathology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... Nucleotidase • ALT ... on but elevated as ... obstruction • ALP
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Cell Carcinoma (RCC ... Symptoms of metastatic ... bone pain and ↑ ALP ... Hypercalcemia 4. ↑ AST, ALT ... , and/or ALP 5.
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... tumor burden • Symptoms
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... Surgical consult ALP ... #Phosphatase #ALP
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
One allele of RB1 ... gene mutated in all ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... adult population: also ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Diagnosis Algorithm Symptoms ... Associated history: Symptoms ... Elevated ALP 2. ... consistent with PBC ... #PBC #Primary
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... postpartum): • Initial symptoms ... Findings: • ↑AST/ALT ... diagnosis #management #pathophysiology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
- Symptoms of ... reported (eg AIH-PBC ... Anti-LKM & Anti-ALC ... immunosuppressive tx: - ALT ... > 10x ULN - ALT
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