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oncology leukemia chronic lymphocytic agglutinin apml classification cold cvid differentiation disease hemeonc hemolytic hodgkins immunodeficiency immunology key lymphoma morphology nephrology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... organ or stem cell ... Scleroderma renal crisis ... anemia" • HELLP ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology Atlas ... uremic syndrome ... #key #diagnosis ... #differential # ... hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... Diagnosis: • ... • Neutropenia, anemia ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... Agranulocytosis • Hypogammaglobulinemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... anemia) • Systemic ... #immunology #hematology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... symptoms - most common ... Diagnosis: • hemolytic ... #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... immunophenotype Clinical ... Infection due to hypogammaglobulinemia ... Leukemia #oncology #hematology ... #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... • Induce blast cell ... initiation • Differential ... #management #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
(SRC) Clinical ... microangiopathic hemolytic ... anemia (MAHA) ... Pathophysiology ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... (NSHL) - (most common ... classification #hematology ... #oncology #management
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