9 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
/ Complications ... • Secondary glaucoma ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
lights are a key symptom ... blindness Signs / Symptoms ... / Complications ... #pathophysiology ... #ophthalmology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Lymphomas • Other hematologic ... #NonHodgkins #comparison ... #oncology #diagnosis ... #differential #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Splenomegaly 5) Symptoms ... thrombocytopenia Complications ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... kinase (BTK) Complications ... leukemia • GI complications ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis