21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #treatment #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Pulmonary Disease Neurologic ... Depression • Multiple Sclerosis ... Chronic Fatigue Syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... and petechiae Causes ... Treatment: ... #oncology #hematology
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
Alexia Without Agraphia ... Alexia without ... is being read (alexia ... MoiseyWoisey #Alexia ... #neurology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and pernicious anemia ... Pathophysiology ... Clinical Manifestations ... disease, Multiple sclerosis ... #treatment #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... stimulation Clinical ... Treatment: • ... #diagnosis #management ... #neurology #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Guillain-Barre Clinical ... #diagnosis #management ... #treatment #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology