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diagnosis glomerular glomerulonephritis hematology immunology nephrology nephrotic workup abnormal ammonia arrhythmias bleeding bruising c5c9deficiency cardiology coagulation disease druginduced edema enzymes
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
response: The complement ... pathway is a non-specific ... alternative, or lectin pathway ... cascade -> MAC ... #pathophysiology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
the Coagulation Cascade ... and intrinsic pathways ... Initiation phase caused ... models (i.e. common pathway ... models #hematology #pathophysiology
Arrhythmias - Differential Diagnosis Algorithm May present as: palpitations, dizziness, syncope, chest discomfort Cardiac Causes: - Structural
Arrhythmias - Differential ... Diagnosis Algorithm ... • Accessory pathway ... Arrhythmias #Cardiology #Differential ... #Diagnosis #Algorithm
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... discern these causes
Drug-Induced Edema Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Activation of the complement ... cascade By ... #Differential # ... Pharmacology #Pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
neurotransmitter pathways ... methionine (SAM) pathway ... Manic #Secondary #Causes ... #Differential # ... Diagnosis #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
its excretory pathway ... although hepatic causes ... namely, the many causes ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... the classical pathway ... (see Complement ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... determine choice of pathway ... decision for repeat testing ... for users of the pathway ... Liver #Enzymes #Differential
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