13 results
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... staining (lg + complement ... MGPN • Complement ... pathway • C3
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... infections • Clinical ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... infections are common causes ... #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. 6) SPEP ... infections are common causes ... diagnosis #initial #testing
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... • Inflammatory Pathway ... cyclophosphamide • Ischemic Pathway
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... activation • Complement ... the classical pathway ... (see Complement ... Humoral #Immunity #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Pathogenesis and clinical ... findings • Polyol Pathway ... enters Polyol pathway ... • Hexosamine Pathway ... Glycosylation - AGE cause
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... determine choice of pathway ... decision for repeat testing ... for users of the pathway ... LFTs #Abnormal #Algorithm
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
The Inhibited Pathway ... caused by N2O, ... use of N2O can cause ... The classic clinical ... #Pathophysiology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Through 2 Different Pathways ... Syndrome: • Clinical ... • Low serum C4 complement