6 results
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... staining (lg + complement ... MGPN • Complement ... pathway • C3
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... infections are common causes ... #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. 6) SPEP ... infections are common causes ... diagnosis #initial #testing
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... • Inflammatory Pathway ... cyclophosphamide • Ischemic Pathway ... cerebritis #diagnosis #management
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... Rapoport-Leubering pathway ... Phosphate is a cause ... renal phosphorus wasting ... respiratory #hypoxia #pathophysiology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... JAK-STAT signaling pathway ... • Treatment algorithms ... hematology #diagnosis #management