7 results
nephrology glomerular glomerulonephritis nephrotic renal testing workup child disease gammopathy histiocytosis hypophosphatemia hypoxia initial langerhans lch limping management membranoproliferative mgrs
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... MGPN • Complement ... pathway • C3 ... immune deposits on EM ... MPGN #nephrology #diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
BEARING CHILD PATHWAY ... Haematology - Sickle cell ... #Limping #NWB #Algorithm ... #Pathway #Child ... Peds #Pediatrics #Diagnosis
Hypophosphatemia and Hypoxia - Pathophysiology ↓ Phosphate leads to ↓ red cell 2,3-DPG and a reduction
and Hypoxia - Pathophysiology ... leads to ↓ red cell ... Rapoport-Leubering pathway ... leads to a ↓ red cell ... Phosphate is a cause
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
decreased red cell ... or alternative complement ... pathways. ... infections are common causes ... testing #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
decreased red cell ... or alternative complement ... pathways. 6) SPEP ... infections are common causes ... disease #workup #diagnosis
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... light-chain ratio Diagnostic ... tubulopathy) - Complement ... pathway activation ... #Significance #Diagnosis
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
driven by MAPK pathway ... Incidence: 4–5 cases ... Birbeck granules (EM ... DIAGNOSIS • Imaging ... Histiocytosis #Diagnosis
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