8 results
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
and intrinsic pathways ... Contemporary Model ... upon intrinsic X-ase ... (i.e. common pathway ... #hematology #pathophysiology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin (extrinsic pathway ... FXIIa (intrinsic pathway ... PTT #diagnosis #models ... #hematology #pathophysiology ... Edoxaban #heparin #pathway
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
deficient patients are ... response: The complement ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
Pathophysiology of ACE inhibitor-induced angioedema: Angioedema is a vascular reaction associated with tissue (subcutaneous, submucosal) edema
Pathophysiology ... of ACE inhibitor-induced ... through alternative pathways ... Pathophys #EM #IM ... Kininogen #Bradykinin #ACE
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Antigens (Ag) are ... molecules that are ... the classical pathway ... sites (e.g. lymph nodes ... Humoral #Immunity #pathophysiology
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
in preclinical models ... GVHD in murine models ... different signaling pathways ... #Pathophysiology ... #IM #Honc #Pharm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... indicate the initial evaluation ... history alongside evaluation ... determine choice of pathway ... for users of the pathway
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
concerns from young age ... Factors • Reward Pathway ... response of reward pathways ... Appearance over-evaluation ... BulimiaNervosa #pathophysiology