7 results
diagnosis nephrology glomerulonephritis hematology nephrotic workup bleeding bruising c5c9deficiency coagulation differential disease hemostasis hypophosphatemia hypoxia immunology initial membranoproliferative models mpgn
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... staining (lg + complement ... MGPN • Complement ... pathway • C3
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
response: The complement ... pathway is a non-specific ... alternative, or lectin pathway ... cascade -> MAC ... #pathophysiology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
the Coagulation Cascade ... and intrinsic pathways ... Initiation phase caused ... models (i.e. common pathway ... models #hematology #pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... infections are common causes ... #testing #workup
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... discern these causes
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. 6) SPEP ... infections are common causes ... diagnosis #initial #testing
Hypophosphatemia and Hypoxia - Pathophysiology ↓ Phosphate leads to ↓ red cell 2,3-DPG and a reduction
and Hypoxia - Pathophysiology ... Rapoport-Leubering pathway ... Phosphate is a cause ... renal phosphorus wasting ... respiratory #hypoxia #pathophysiology
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