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rheumatology differential management disease glomerular glomerulonephritis nephrology nephrotic vasculitis workup abnormal bleeding bruising calcium cascade cerebritis child classification cns coagulation
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
BEARING CHILD PATHWAY ... FLAGS - In all cases ... #Limping #NWB #Algorithm ... #Pathway #Child ... Peds #Pediatrics #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... #differential #diagnosis ... #algorithm #rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... activate inflammatory pathways ... Synovial Fluid Testing ... Gout #Comparison #rheumatology ... #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... • Inflammatory Pathway ... cyclophosphamide • Ischemic Pathway
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... #Hematology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
and intrinsic pathways ... Initiation phase caused ... models (i.e. common pathway ... #models #hematology ... #pathophysiology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... determine choice of pathway ... decision for repeat testing ... for users of the pathway ... #Hepatology #Liver
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... infections are common causes ... #workup #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Through 2 Different Pathways ... Labs/Diagnosis: ... • Low serum C4 complement
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... activate inflammatory pathways ... culture used to diagnose ... Deposition #Disease #Rheumatology ... #diagnosis #management
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