14 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Formation -> Vasculitis ... #HUV #Pathophysiology
Antiemetics and Vomiting

#Pathophysiology #Antiemetics #Locations #Action #Pathways #Nausea #Chemotherapy #TriggerZone #CTZ
and Vomiting #Pathophysiology ... Antiemetics #Locations #Action ... #Pathways #Nausea
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Hypotension Mesolimbic Pathway ... Mesocortical Pathway ... Tuberoinfundibular Pathway ... Nigrostriatal Pathway ... , and/or limbs caused
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Mesangiocapillary GN • Active ... dysmorphic RBC, RBC casts ... staining (lg + complement ... MGPN • Complement ... pathway • C3
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... discern these causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Through 2 Different Pathways ... • Low serum C4 complement ... • Vasculitis
Priapism: Pathogenesis

 - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
erection-ending) pathways ... norepinephrine action ... Prolonged erection lasting ... #Priapism #Pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... infections are common causes ... for ANCA-related vasculitis
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
The Inhibited Pathway ... caused by N2O, ... decrease in the active ... use of N2O can cause ... #Pathophysiology