12 results
Complement Pathways
- Classical Pathway
- Lectin Pathway
- Alternative Pathway

#Complement #Pathway #hematology #pathophysiology
Complement Pathways ... - Classical Pathway ... - Lectin Pathway ... #Pathway #hematology ... #pathophysiology
Overview of the Complement System - Classical and Alternative Pathways

by Dr.Grace Leo @gracie_leo

#Complement #System #Classical #Alternative
Overview of the Complement ... System - Classical ... and Alternative Pathways ... #Alternative #Pathways ... #Pathophysiology
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram
Humoral Immunity:
 •
: • Classical ( ... by antibodies) pathway ... Mannose-binding Lectin pathway ... • Alternative pathway ... #differential #diagnosis
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
response: The complement ... pathway is a non-specific ... Bacterial infection -> Classical ... alternative, or lectin pathway ... #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... proteins via the classical ... pathway (see Complement ... Humoral #Immunity #pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... To propose new classifications ... IFN #signature #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
that activate the classical ... or alternative complement ... pathways. ... testing #workup #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... Labs/Diagnosis: ... • Low serum C4 complement ... Cryoglobulins #diagnosis ... #types #classification