9 results
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
present Ag to CD4 ... activation • Complement ... the classical pathway ... (see Complement ... Humoral #Immunity #pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... To propose new classifications ... IFN #signature #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
migrate by various pathways ... LifeCycle #Parasite #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... Labs/Diagnosis: ... • Low serum C4 complement ... Cryoglobulins #diagnosis ... #types #classification
Strongyloides Stercoralis Lifecycle
Free-Living Cycle:
1) Rhabditiform larvae in the intestine are excreted in stool. 
2) Development into
migrate by various pathways ... stercoralis #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... reported to the CDC ... /pdfs/smallpox-diagnostic-algorithm-poster ... See table below
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
JAK-STAT signaling pathway ... Splenomegaly Diagnosis ... : On the CBC, ... A conclusive diagnosis ... • Treatment algorithms
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
light-chain ratio Diagnostic ... guide subtype classification ... tubulopathy) - Complement ... pathway activation ... #Significance #Diagnosis