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rheumatology management types allergy calcium comparison cryoglobulinemia cryoglobulins deposition disease gammopathy gout hypersensitivity ifn interferon mgrs monoclonal pseudogout pyrophosphate reactions
The interferon (IFN) signature: what’s the point? How to use it in clinical practice? Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... To propose new classifications ... IFN #signature #diagnosis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... activate inflammatory pathways ... culture used to diagnose ... stain and culture- Diagnose ... #rheumatology #Diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... Labs/Diagnosis: ... • Low serum C4 complement ... Cryoglobulins #diagnosis ... #types #classification
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... calcium to form CPP ... activate inflammatory pathways ... culture used to diagnose ... #Rheumatology #diagnosis
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
light-chain ratio Diagnostic ... guide subtype classification ... tubulopathy) - Complement ... pathway activation ... #Significance #Diagnosis
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