6 results
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... To propose new classifications ... for diseases ... IFN #signature #diagnosis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... activate inflammatory pathways ... culture used to diagnose ... #rheumatology #Diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... (CPPD) Pathophysiology ... activate inflammatory pathways ... culture used to diagnose ... #Rheumatology #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... • Autoimmune diseases ... Labs/Diagnosis: ... • Low serum C4 complement ... #types #classification
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
light-chain ratio Diagnostic ... guide subtype classification ... tubulopathy) - Complement ... pathway activation ... #Significance #Diagnosis