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diagnosis rheumatology vasculitis differential c5c9deficiency child cryoglobulinemia cryoglobulins enzymes essential et gammopathy glomerulonephritis hepatology huv hypocomplementemic immunology lfts limping liver
Complement Pathways - Classical Pathway - Lectin Pathway - Alternative Pathway #Complement #Pathway #hematology #pathophysiology
Complement Pathways ... - Classical Pathway ... - Lectin Pathway ... #Pathway #hematology ... #pathophysiology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
BEARING CHILD PATHWAY ... splenomegaly, abnormal ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... #Pathway #Child
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
fatality is rare Normal ... : The complement ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Idiopathic • Normal ... Complement: IgA ... differential #diagnosis #algorithm ... #rheumatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... determine choice of pathway ... for users of the pathway ... #Algorithm #Hepatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... • Low serum C4 complement ... diagnosis #types #classification ... #rheumatology #
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
meet criteria for hematologic ... kidney function • Abnormal ... guide subtype classification ... tubulopathy) - Complement ... pathway activation
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
JAK-STAT signaling pathway ... are usually near-normal ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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