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diagnosis nephrology glomerulonephritis nephrotic rheumatology testing vasculitis workup cryoglobulinemia cryoglobulins disease hypocomplementemic initial membranoproliferative mpgn nephritic nephritis renal types urticarial
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... staining (lg + complement ... ) • Ex: HCV, HBV ... MGPN • Complement ... pathway • C3
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Urticarial #Vasculitis #HUV ... #Pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... or alternative complement ... pathways. ... antibody, and HIV ... risk factors for HIV
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... or alternative complement ... pathways. 6) SPEP ... antibody, and HIV ... risk factors for HIV
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... • Infections: HCV ... infection, HBV ... • Low serum C4 complement ... diagnosis #types #classification
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