6 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Urticarial #Vasculitis #HUV ... #Pathophysiology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... • Infections: HCV ... infection, HBV ... • Low serum C4 complement ... #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
or alternative complement ... pathways. ... antibody, and HIV ... risk factors for HIV ... cryoglobulinemias (types
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... pathways. 6) SPEP ... antibody, and HIV ... risk factors for HIV ... cryoglobulinemias (types
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... pathway activation ... vasculitis Types