5 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Urticarial #Vasculitis #HUV ... #Pathophysiology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... • Infections: HCV ... infection, HBV ... • Low serum C4 complement ... diagnosis #types #classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
or alternative complement ... pathways. ... antibody, and HIV ... risk factors for HIV ... glomerular #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... pathways. 6) SPEP ... antibody, and HIV ... risk factors for HIV ... glomerular #disease #workup
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... pathway activation