18 results
Complement Pathways
- Classical Pathway
- Lectin Pathway
- Alternative Pathway

#Complement #Pathway #hematology #pathophysiology
Complement Pathways ... - Classical Pathway ... - Lectin Pathway ... #Pathway #hematology ... #pathophysiology
Overview of the Complement System - Classical and Alternative Pathways

by Dr.Grace Leo @gracie_leo

#Complement #System #Classical #Alternative
Overview of the Complement ... System - Classical ... and Alternative Pathways ... #Alternative #Pathways ... #Pathophysiology
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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Arachidonic acid pathway ... #Pharmacology #Pathophysiology ... ArachidonicAcid #Pathways ... #Leukotrienes #Synthesis
Steroid Synthesis Pathway

Dr. Caoimhe Costigan @CaoimheCostigan

#Steroid #Synthesis #pathophysiology #algorithm #endocrinology
Steroid Synthesis ... Pathway Dr. ... CaoimheCostigan #Steroid #Synthesis ... #pathophysiology ... #algorithm #endocrinology
Steroid Synthesis Pathway

(OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
Steroid Synthesis ... Pathway (OH, ... CaoimheCostigan #Steroid #Synthesis ... #Pathway #metabolism ... #pathophysiology
Heme Synthesis Pathway
Enzymes
1. ALA Synthase
2. ALA Dehydratase
3. Porphobilinogen deaminase
4. UP Ill Synthase
5. UP Ill Decarboxylase
6. Coproporphyrinogen
Heme Synthesis Pathway ... JamesCaoMD #Heme #Synthesis ... #Pathway #pathophysiology
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram
Humoral Immunity:
 •
Humoral Immunity and Complement ... : • Classical ( ... by antibodies) pathway ... Mannose-binding Lectin pathway ... • Alternative pathway
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Vasculitis #HUV #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates JAK-STAT pathway ... activates JAK-STAT pathway ... expression/protein synthesis ... Activation of AKT pathway ... endocrinology #pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
response: The complement ... pathway is a non-specific ... Bacterial infection -> Classical ... alternative, or lectin pathway ... #pathophysiology