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hematology management oncology differential mds myelodysplastic syndrome acidosis aplastic bowel common cvid elevation hodgkins hypogammaglobulinemia ibs immunodeficiency immunology infections infectiousdiseases
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... ) Classification ... physical exam, CT ... Hodgkin Lymphoma Treatment ... #classification
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... number of CD34+ cells ... Treatment: ... #oncology #hematology ... #diagnosis #management
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Treatment: • Global ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... and Hepatology ... #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... late adulthood • Diagnosis ... Chest CT: • Ground-glass ... autoimmune hemolytic anemia ... DDX - Other causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... perfusion - shock->treatments ... before beginning treatment ... 30mmHg) - Severe anemia ... #typeb #classification
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... including white blood cell ... #causes #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Growers (Runyon Classification ... Advanced HIV (CD4 cell ... Bone Marrow - Anemia ... Imaging, high res CT
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • 18F-FDG PET/CT ... • No CRAB - no anemia ... Bone marrow Treatment ... #Workup #Hematology
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