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diagnosis management oncology algorithm causes secondary generalized pruritus rheumatology signs symptoms activation aplastic arteritis behcet cancer chronic cll disease dress
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... #Diagnosis #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Iron deficiency anemia ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... ie petechiae), Neutropenia-specific ... Rash #oncology #differential ... MINTC #Mnemonic #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
- Generalized Differential ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology ... #Differential #
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... , Kostmann syndrome ... Megaloblastic anemia-rare ... diagnosis #causes #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Difficulty breathing • Neutropenia ... Constitutional Syndromes ... Treatment: ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... microglobulin Treatment ... workup #oncology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease • Neutropenia ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology
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