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oncology management algorithm causes chronic classification cll gap globulin hodgkins leukemia lymphocytic mds myelodysplasia myelodysplastic platelets protein proteingap syndromes thrombocytosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... , Lymphoma, Rebound ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Difficulty breathing • Neutropenia ... anemia Treatment ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... , anemia, thrombocytopenia ... Pure red cell aplasia ... #workup #oncology ... #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... white blood cell aplasia ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Workup: • Full ... Immunohistochemical studies (to differentiate ... Treatment • Early ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... #diagnosis #hematology
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