35 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... pylori test (GI symptoms ... function test, ANA ... anti-phospholipid antibodies ... Causes #Workup #hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(ANA) ANA or Anti-NucIear ... context of other symptoms ... likely it will be clinically ... Lymphoproliferative Disorders ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... • Rule out B12 and ... Algorithm #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... - Coagulation disorder ... Wernicke-Korsakoff syndrome ... #diagnosis #signs ... #symptoms #nutrition
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
autoimmune disorder ... Clinical Picture ... life-threatening Differential ... test - Cogan sign ... - Peek sign
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Pemphigoid - Diagnosis and ... Management Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... Diagnosis #Management #dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... and Symptoms: ... , breast CA - Hematologic ... #diagnosis #dermatology