6 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Seizures • Rhabdomyolysis ... Treatment - ... #nephrology #management ... #pathophysiology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... tubal acidosis and metabolic ... alkalosis, Ketonuria ... , UNa < 20 • Nephrotic ... #Causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Alkalosis: Emesis ... , Diuretics, Bartter ... syndrome, Gitelman ... #nephrology #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... alkalosisKidney ... , Gitelman syndrome ... the indicated causes ... #nephrology #differential
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... alkalosis • Familial ... syndromeHyponatremia ... stones caused by ... #Nephrology #Pharmacology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Heat stroke - Metabolic ... nephrotoxicity to kidney ... Monitor potassium ... Loop diuretics for ... #treatment #nephrology