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oncology management anemia aplastic algorithm chronic cll gap hodgkins lymphocytic lymphoma mds myelodysplasia myelodysplastic protein proteingap syndromes thrombocytopenia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
: • Recurrent infections ... • Mucosal bleeding ... from low platelets ... (antithymocyte globulin ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... Myelofibrosis Infectious ... • Rheumatic disorders ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... #Disorders #Differential ... #Diagnosis #Causes ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... increase in gamma globulins ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease • Neutropenia ... • Platelet Disorders ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Include: • Viral infections ... Connective tissue disorders ... gastric tumors • Hematology ... #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... antithymocyte globulin ... Anemia #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... Hodgkin Lymphoma Workup ... - Low Hb and platelets ... #hematology #oncology
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