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algorithm oncology allergy anemia classification enlarged hodgkins leukemia lymphoma management mds myelodysplasia myelodysplastic secondary spleen splenomegaly syndromes testing tryptase
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... of eosinophilia ... glucocorticoid treatment ... #Differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... ): • Acute infection ... iron deficiency, hemolysis ... Diagnosis #Causes ... #hematology #secondary
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Infectious • ... Myeloproliferative disorders ... vera, essential thrombocytosis ... Serum Sickness Hemolytic ... #Causes #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... - Differential ... hypertension and/or drug treatment ... diagnosis #causes ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... thalassemia, S Lepore • Basophilic ... inclusions - If infection ... Consider RBC membrane disorder ... #workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... , basophilia, and ... thrombocytosis) ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
ESRD & CAD • Eosinophilic ... GI Disorders ... • Parasitic infections ... : • Mast cell ... #Diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... classification #hematology
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