8 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... - Acute Viral Hepatitis ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... function may be abnormal ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... - If both are normal ... of ALP • Near normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
immunosuppression • Acute ... with severe liver injury ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... • Warfarin • Acute ... if not already performed ... Liver disease • Acute ... #Diagnosis #Hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... pattern of liver injury ... upper limit of normal ... AIH #Diagnosis #Management ... #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Rare: DAH, acute ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Mediastinal mass) • CT ... Immunohistochemical studies (to differentiate ... physical exam, CT ... classification #hematology ... #oncology #management