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diagnosis hematology causes hyperkalemia algorithm high peds anemia bleeding classification nephrology purpura thrombocytosis agglutinin alte atlas bariatric bloodcell brue bruising
Bleeding disorders in children #Bleeding #Disorders #Differential #Hematology #Pediatrics #Peds
Bleeding disorders ... children #Bleeding #Disorders ... #Differential # ... Hematology #Pediatrics
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Recent IV potassium ... - Hyperkalemia Periodic ... #hyperkalemia #differential ... diagnosis #causes #potassium
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Recent IV potassium ... - Hyperkalemia Periodic ... #hyperkalemia #differential ... diagnosis #causes #potassium
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... Algorithm #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... younger pts) Differential ... Monoclonal IgM Includes Disorders ... #anemia #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... : • Hemolytic ... acquired, drug) • Periodic ... paralyses CNS Disorders ... Dehydrogenase #Elevated #differential
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm Cardiac: • Congenital Heart Disease •
Event (ALTE) - Differential ... Neuromuscular • Disorders ... Proxy Apnea: • Periodic ... Event #ALTE #BRUE #Differential ... #Causes #Peds #Pediatrics
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